Combining Fonts

Assignment: Type out two fonts (A–Z, 0–9) and smash them together, splice their DNA. Take the spine from one, and mesh it with the stems or serifs of another. Create two sets of upper-case letters, and numbers 0-9.

I have googled, YouTubed, searched on Adobe. I'm having a problem figuring out how to "splice" the text and combine it. Any suggestions?

Thanks!